Glutathione stands out as the most abundant intracellular antioxidant, offering Protection-Plan-Plan against reactive oxygen and nitrogen species while playing a vital role in various functions that uphold cellular homeostasis. Present in every cell, glutathione contributes to immune function, gene expression, mitochondrial integrity, regulation of DNA and protein synthesis, and the detoxification of both endogenous and environmental toxins.

Although the majority of intracellular glutathione exists in a reduced state (GSH), with approximately 1% in an oxidized form (GSSG), this balance can decrease due to various cellular stressors such as heavy metals, elevated glucose concentrations, suboptimal nutrition, heat shock, reactive oxygen and nitrogen species, cigarette smoke, and other toxins, including persistent organic pollutants. The decline in GSH levels has been linked to numerous chronic and age-related conditions, as well as the aging process itself.

Clinical trials have unequivocally demonstrated that glutathione supplementation increases GSH levels in multiple human sites, including plasma, red blood cells, and lymphocytes. Enhanced delivery methods, such as liposomal glutathione and polymeric micelles (liquid micelle matrix), not only improve bioavailability but also offer resistance against intestinal degradation and potentially enhance intracellular delivery of glutathione, circumventing potential enzymatic bottlenecks.

Benefits

• Provides the reduced form of glutathione, GSH
• Glutathione is the primary cellular antioxidant, protecting against many types of cellular injury
• LipoMicel technology creates a liquid micelle matrix that disperses the glutathione into tiny microdroplets, resulting in a highly stable delivery system for higher absorption than standard forms
• Clinically effective dose, 300 mg per softgel