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S-Adenosyl-L-Methionine (SAMe) is a natural compound and methyl group donor that supports the methylation cycle, a process which is essential for many aspects of health. Methylation is fundamental for ridding the body of certain toxins, and certain people, such as those with chronic liver disorders, cannot produce adequate levels of SAMe.
SAMe’s effectiveness to support a balanced mood is demonstrated by many clinical studies. SAMe is in fact so effective for boosting a low mood that it is legally registered as a prescription drug in several European countries for mood balance. One study showed that SAMe was as effective as a common prescription medication for mood. It is thought that SAMe works by help boosting serotonin, dopamine and melatonin levels in the brain, low levels of which are commonly associated with mood imbalances such as anxiety and depression. SAMe has also been found to support joint health in osteoarthritis patients as effectively as a popular anti-inflammatory drug by reducing inflammation and protecting joint tissue from degradation.
AOR introduced the first SAMe supplement to Canada in 2000. SAMe can provide mood support, benefit those suffering from osteoarthritis, and is essential for those with liver disorders to maintain good health. AOR’s SAMe 400 provides an effective dosage and a stable form of this valuable compound in an enteric coated tablet for maximum effectiveness.
AOR™ guarantees that all ingredients have been declared on the label. Contains no wheat, gluten, nuts, peanuts, sesame seeds, sulphites, mustard or dairy.
The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide or replace medical advice to individuals from a qualified health care professional. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.
Take two or three tablets daily on an empty stomach, or as directed by a qualified health care practitioner. Use for a minimum of four weeks to see beneficial effects for osteoarthritic pain and a minimum of two weeks for mood support.
Do not take at night, since this product may cause anxiety, restlessness and insomnia. Consult a health care practitioner prior to use if you are pregnant or breastfeeding, suffer from depression or are taking medications which may influence serotonin levels (e.g. antidepressants).
I used to take GNC SAMe, the only SAMe that would work for me, but it became unavailable in Canada so that left me to search for another brand. When I came across AOR SAMe the price deterred me from buying it at first but I'm so glad I broke down and tried it. Because of the price, I don't know how long I'll be able to continue taking this product but it works well for mood and body aches.
I take the 400mg
I can't comment on whether this is 'working' but the product seems to be high quality and well packaged. Arrived quickly and in good condition.
This product is great, helps very much with mood swings. Skip buying takeout coffee and spend your money and something that is good for you!!
I use this product for depression and wouldn't be without it.
I searched for a SAME supplement without Malitol and in a blister package. I kept coming back to AOR brand. I have not been using it long enough to notice a difference. However there has been no tummy troubles like other have said can be associated with SAMe. This can be because of better quality product or no Malitol in the ingredients.
This has helped my husband tremendously with his S.A.D. We will definitely purchase as needed.
I find that SAMe ( in the AOR metallic foil blister pack), in combination with Curcumin (AOR) is the only thing that brings relief for my osteoarthritis. I have been taking these supplements for about three years now, and my osteoarthritis pain symptoms have virtually disappeared. A couple of other sufferers that I have convinced to try SAMe (without the curcumin) have reported the same results: they are thrilled with the way SAMe has made their pain "go away". I cannot recommend this product more highly for the relief of pain associatied with osteoarthritis.
SAMe is a very powerful and effective supplement for moods (anxiety, depression, stress). This is a serious supplement and you should talk to a health care provider if you intend on taking it for long term (ie: 6 months or more). However it is very expensive in Canada. If you cannot afford it try 5-htp or St. Johns Wort which work almost as good but at a cheaper price. Note: SAMe can raise homocysteine levels (which is not good for the heart) if taken at high does for a long duration. However, this can be offset by taking a Vitamin B complex daily which lowers homocysteine level.
I just started and was told 4-6 weeks is where I will see the benefits. I'm taking this 2x a day on an empty stomach, for my knee.
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